Synthetic coordination chemistry of transition metal ions and ligand design is central to our work with focus on new Fe(II) spin equilibria systems using pyridyl/pyrazole/imidazole-containing chelating ligands, stabilization of ligands, stabilization of high-valent iron, manganese, and nickel complexes and stabilization of ligand cation-radical complexes of deprotonated pyridine/pyrazine amide ligands, magneto-structural coorelations, design of anion receptors, and bioinorganic synthetic model complexes of metalloenzyme active sites (dioxygen activation, water oxidation, hydrolysis of substrates, and metal–coordinated phenoxyl radical complexes) using tailor-made ligands, and half-sandwich organometallic molecules. We also have interest in coordinaton polymers. Research covers extensive synthesis, molecular structural (X-ray cry
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Research Interests
Dr. Veena K Parnaik's research interests are directed towards understanding the functional role of the nuclear lamina, an essential component of nuclear architecture in metazoan cells. She has identified distinctive lamin domains that colocalize with RNA splicing factor compartments and are involved in the spatial organization of transcription and pre-mRNA splicing. She has shown that the internal lamina is reorganized specifically during muscle differentiation in a process mediated by cyclin D3 and pRb. Interestingly, cyclin D3 can bind directly to lamin A; this supports the emerging concept that lamins influence specific signalling pathways by sequestration of key regulatory factors. Her studies demonstrate that lamin A mutations impair muscle differentiation and DNA repair pathways and current work is aimed at addressing how this occurs. Dr. Parnaik`s findings have given important mechanistic insights into the role of lamin mutations in de
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Journal
Year
Anaemia and iron deficiency in India: a venous blood-based survey of adolescents, adults, and the elderly in eight states
European Journal of Clinical Nutrition (Accepted)
2024
Investigating misclassification of type 1 diabetes in a population- based cohort of British Pakistanis and Bangladeshis using polygenic risk scores
Scientific Reports (Accepted)
2024
Maternal age is related to offspring DNA methylation: a meta-analysis of results from the PACE consortium
Aging Cell (Accpted)
2024
Maternal peri-conceptional vitamin B12 deficiency in Wistar rats leads to sex-specific programming for cardiometabolic disease risk in the next generationÂ
The Journal of Nutrition (Accepted)
2023
Genetic architecture of adiposity measures among Asians: Findings from GWAS
Annals of Human Genetics
2023
DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood
Nature Communications (Accepted)
2023
Differential expression of genes influencing mitotic processes in cord blood mononuc